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| Symptoms and Diagnosis |
Patients with Restless Legs Syndrome (RLS) may only initially report sleep complaints rather than leg symptoms to their healthcare provider. [10] In the diagnosis of Restless Legs Syndrome, healthcare providers should look beyond a sleep complaint and ask whether their patients’ legs are keeping them from falling asleep.
The International Restless Legs Syndrome (IRLS) Study Group developed 4 diagnostic criteria for RLS, which form the basis to either confirm or rule out a diagnosis of RLS. [1] |

*Diagnostic criteria developed by the IRLS Study Group in collaboration with the National Institutes of Health (NIH). |
Uncomfortable Leg Sensations
Uncomfortable leg sensations with RLS may be described using the following terms [1,11]
| –Creeping |
–Aching |
–Painful |
| –Crawling |
–Burning |
–Itching |
| –Tingling |
–Pulling |
–Cramping |
Patients may complain that travel by plane or car becomes increasingly difficult. [1]
The ICD-9 code for RLS is 333.94. RLS is defined in the DSM-IV under section 307.47 [12,13]
Secondary Restless Legs Syndrome
RLS may present as a result of other underlying conditions, eg, secondary RLS. It is important to rule out secondary RLS, which may be related to other underlying conditions, including:[1]
- Iron deficiency
- Pregnancy
- End-stage renal disease (ESRD)
- Various polyneuropathies
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Requip is indicated for patients with moderate-to-severe primary RLS.
Requip has been associated with sedating effects, including somnolence, and the possibility of falling asleep while engaged in activities of daily living, including operation of a motor vehicle. Syncope or symptomatic hypotension may occur, particularly during initial treatment or dose titration. Impulse control symptoms, including pathological gambling and hypersexuality, have been reported in patients treated with dopaminergic agents, including ropinirole.
For More Safety Information about Requip, click here.
Complete Prescribing Information for Requip® (ropinirole HCl) Tablets
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