Introduction

Parkinson’s disease patients have reduced amounts of dopamine in their brain. Dopamine is the chemical messenger involved in processing information about movement in the brain. As Parkinson’s disease progresses to more advanced stages, less and less dopamine is produced and symptoms of Parkinson’s disease become more noticeable.

Levodopa’s Use in Parkinson’s Disease Treatment

Levodopa, or "L-dopa," is a medication that may be prescribed to treat some Parkinson’s disease symptoms. Levodopa turns into dopamine in a patient’s brain.

The "Wearing-Off" Effect

Patients who take Parkinson's disease medication(s) for the long-term treatment of their symptoms may experience the "wearing-off" effect. As symptoms progress in a patient, the amount of medication required to keep them under control may increase. "Wearing off" episodes occur when the benefit of a given dose of medication wanes and no longer lasts until the next dose.

Role of REQUIP in Reducing "Wearing-Off" Effect

REQUIP helps improve control over various body movements, which begin to slow or become irregular in Parkinson’s disease. REQUIP also helps reduce the daily time period when treatment often wears off or is not as effective. REQUIP can help you maintain your ability to do daily activities, such as walking, writing, talking, and dressing.